The Wealth Index is based on a number of indicators of affluence including average household income and average net worth, but it also includes the value of material possessions and resources. It represents the wealth of the area relative to the national level. Values above or below 100 represent above-average wealth or below-average wealth compared to the national level.
| Name | County | Wealth Index | |
|---|---|---|---|
| 1. | City View Census Designated Place | Greenville | 23 |
| 2. | Gayle Mill Census Designated Place | Chester | 23 |
| 3. | Judson Census Designated Place | Greenville | 23 |
| 4. | East Gaffney Census Designated Place | Cherokee | 25 |
| 5. | South Sumter Census Designated Place | Sumter | 26 |
| 6. | Watts Mills Census Designated Place | Laurens | 26 |
| 7. | Town of Scotia | Hampton | 27 |
| 8. | Town of Vance | Orangeburg | 27 |
| 9. | Town of Fairfax | Allendale | 27 |
| 10. | City of Bishopville | Lee | 27 |
| 11. | City of Denmark | Bamberg | 28 |
| 12. | Town of Eutawville | Orangeburg | 28 |
| 13. | Wilkinson Heights Census Designated Place | Orangeburg | 28 |
| 14. | Saxon Census Designated Place | Spartanburg | 29 |
| 15. | Town of Blackville | Barnwell | 29 |
| 16. | Town of Allendale | Allendale | 29 |
| 17. | City of Bennettsville | Marlboro | 30 |
| 18. | Homeland Park Census Designated Place | Anderson | 30 |
| 19. | Town of Livingston | Orangeburg | 30 |
| 20. | Town of Neeses | Orangeburg | 30 |
