| Area | Census 2000 | 7/1/2008 | Absolute Change | Relative Change |
| South Carolina | 4,012,012 | 4,479,800 | 467,788 | 11.66% |
|---|---|---|---|---|
| Abbeville city | 5,840 | 5,547 | -293 | -5.02% |
| Aiken city | 25,337 | 29,434 | 4,097 | 16.17% |
| Allendale town | 4,052 | 3,659 | -393 | -9.70% |
| Anderson city | 25,514 | 27,027 | 1,513 | 5.93% |
| Andrews town | 3,068 | 2,978 | -90 | -2.93% |
| Arcadia Lakes town | 882 | 836 | -46 | -5.22% |
| Atlantic Beach town | 351 | 397 | 46 | 13.11% |
| Awendaw town | 1,195 | 1,189 | -6 | -0.50% |
| Aynor town | 587 | 640 | 53 | 9.03% |
| Bamberg town | 3,733 | 3,432 | -301 | -8.06% |
| Barnwell city | 5,035 | 4,783 | -252 | -5.00% |
| Batesburg-Leesville town | 5,517 | 5,580 | 63 | 1.14% |
| Beaufort city | 12,950 | 11,755 | -1,195 | -9.23% |
| Belton city | 4,461 | 4,670 | 209 | 4.69% |
| Bennettsville city | 9,425 | 9,012 | -413 | -4.38% |
| Bethune town | 352 | 370 | 18 | 5.11% |
| Bishopville city | 3,670 | 3,859 | 189 | 5.15% |
| Blacksburg town | 1,880 | 1,903 | 23 | 1.22% |
| Blackville town | 2,973 | 2,837 | -136 | -4.57% |
| Blenheim town | 137 | 128 | -9 | -6.57% |
| Bluffton town | 1,275 | 4,312 | 3,037 | 238.20% |
| Blythewood town | 170 | 1,407 | 1,237 | 727.65% |
| Bonneau town | 354 | 352 | -2 | -0.56% |
| Bowman town | 1,198 | 1,149 | -49 | -4.09% |
| Branchville town | 1,083 | 1,035 | -48 | -4.43% |
| Briarcliffe Acres town | 470 | 548 | 78 | 16.60% |
| Brunson town | 589 | 571 | -18 | -3.06% |
| Burnettown town | 2,720 | 2,665 | -55 | -2.02% |
| Calhoun Falls town | 2,303 | 2,183 | -120 | -5.21% |
| Camden city | 6,682 | 7,033 | 351 | 5.25% |
| Cameron town | 449 | 407 | -42 | -9.35% |
| Campobello town | 449 | 586 | 137 | 30.51% |
| Carlisle town | 496 | 458 | -38 | -7.66% |
| Cayce city | 12,150 | 12,646 | 496 | 4.08% |
| Central Pacolet town | 267 | 280 | 13 | 4.87% |
| Central town | 3,522 | 4,104 | 582 | 16.52% |
| Chapin town | 628 | 709 | 81 | 12.90% |
| Charleston city | 96,650 | 111,978 | 15,328 | 15.86% |
| Cheraw town | 5,524 | 5,427 | -97 | -1.76% |
| Chesnee city | 1,003 | 1,078 | 75 | 7.48% |
| Chester city | 6,476 | 6,045 | -431 | -6.66% |
| Chesterfield town | 1,318 | 1,318 | 0 | 0.00% |
| Clemson city | 11,939 | 13,012 | 1,073 | 8.99% |
| Clinton city | 8,091 | 8,892 | 801 | 9.90% |
| Clio town | 774 | 721 | -53 | -6.85% |
| Clover town | 4,014 | 4,916 | 902 | 22.47% |
| Columbia city | 116,278 | 127,029 | 10,751 | 9.25% |
| Conway city | 11,788 | 15,894 | 4,106 | 34.83% |
| Cope town | 107 | 102 | -5 | -4.67% |
| Cordova town | 157 | 151 | -6 | -3.82% |
| Cottageville town | 707 | 677 | -30 | -4.24% |
| Coward town | 650 | 676 | 26 | 4.00% |
| Cowpens town | 2,279 | 2,413 | 134 | 5.88% |
| Cross Hill town | 601 | 583 | -18 | -3.00% |
| Darlington city | 6,720 | 6,666 | -54 | -0.80% |
| Denmark city | 3,328 | 3,005 | -323 | -9.71% |
| Dillon city | 6,316 | 6,353 | 37 | 0.59% |
| Donalds town | 354 | 335 | -19 | -5.37% |
| Due West town | 1,209 | 1,268 | 59 | 4.88% |
| Duncan town | 2,870 | 3,118 | 248 | 8.64% |
| Easley city | 17,754 | 20,325 | 2,571 | 14.48% |
| Eastover town | 830 | 779 | -51 | -6.14% |
| Edgefield town | 4,449 | 4,418 | -31 | -0.70% |
| Edisto Beach town | 641 | 718 | 77 | 12.01% |
| Ehrhardt town | 614 | 552 | -62 | -10.10% |
| Elgin town | 806 | 1,256 | 450 | 55.83% |
| Elko town | 212 | 206 | -6 | -2.83% |
| Elloree town | 742 | 699 | -43 | -5.80% |
| Estill town | 2,425 | 2,322 | -103 | -4.25% |
| Eutawville town | 344 | 328 | -16 | -4.65% |
| Fairfax town | 3,206 | 3,158 | -48 | -1.50% |
| Florence city | 30,248 | 31,570 | 1,322 | 4.37% |
| Folly Beach city | 2,116 | 2,412 | 296 | 13.99% |
| Forest Acres city | 10,558 | 9,925 | -633 | -6.00% |
| Fort Lawn town | 864 | 810 | -54 | -6.25% |
| Fort Mill town | 7,587 | 10,032 | 2,445 | 32.23% |
| Fountain Inn city | 6,017 | 7,760 | 1,743 | 28.97% |
| Furman town | 286 | 278 | -8 | -2.80% |
| Gaffney city | 12,968 | 13,200 | 232 | 1.79% |
| Gaston town | 1,304 | 1,442 | 138 | 10.58% |
| Georgetown city | 8,950 | 8,501 | -449 | -5.02% |
| Gifford town | 370 | 355 | -15 | -4.05% |
| Gilbert town | 500 | 594 | 94 | 18.80% |
| Goose Creek city | 29,208 | 37,900 | 8,692 | 29.76% |
| Govan town | 67 | 62 | -5 | -7.46% |
| Gray Court town | 1,021 | 987 | -34 | -3.33% |
| Great Falls town | 2,194 | 2,043 | -151 | -6.88% |
| Greeleyville town | 452 | 397 | -55 | -12.17% |
| Greenville city | 56,002 | 59,988 | 3,986 | 7.12% |
| Greenwood city | 22,071 | 22,533 | 462 | 2.09% |
| Greer city | 16,843 | 24,557 | 7,714 | 45.80% |
| Hampton town | 2,837 | 2,754 | -83 | -2.93% |
| Hanahan city | 12,937 | 16,065 | 3,128 | 24.18% |
| Hardeeville city | 1,793 | 2,763 | 970 | 54.10% |
| Harleyville town | 594 | 689 | 95 | 15.99% |
| Hartsville city | 7,556 | 7,465 | -91 | -1.20% |
| Heath Springs town | 864 | 1,044 | 180 | 20.83% |
| Hemingway town | 573 | 500 | -73 | -12.74% |
| Hickory Grove town | 337 | 422 | 85 | 25.22% |
| Hilda town | 436 | 420 | -16 | -3.67% |
| Hilton Head Island town | 33,862 | 33,913 | 51 | 0.15% |
| Hodges town | 158 | 167 | 9 | 5.70% |
| Holly Hill town | 1,281 | 1,344 | 63 | 4.92% |
| Hollywood town | 3,946 | 4,398 | 452 | 11.45% |
| Honea Path town | 3,504 | 3,674 | 170 | 4.85% |
| Inman city | 1,884 | 2,096 | 212 | 11.25% |
| Irmo town | 11,039 | 11,684 | 645 | 5.84% |
| Isle of Palms city | 4,583 | 4,678 | 95 | 2.07% |
| Iva town | 1,156 | 1,200 | 44 | 3.81% |
| Jackson town | 1,625 | 1,647 | 22 | 1.35% |
| Jamestown town | 97 | 102 | 5 | 5.15% |
| Jefferson town | 704 | 693 | -11 | -1.56% |
| Johnsonville city | 1,418 | 1,491 | 73 | 5.15% |
| Johnston town | 2,336 | 2,336 | 0 | 0.00% |
| Jonesville town | 982 | 901 | -81 | -8.25% |
| Kershaw town | 1,645 | 1,947 | 302 | 18.36% |
| Kiawah Island town | 1,163 | 1,118 | -45 | -3.87% |
| Kingstree town | 3,496 | 3,248 | -248 | -7.09% |
| Kline town | 238 | 231 | -7 | -2.94% |
| Lake City city | 6,478 | 6,666 | 188 | 2.90% |
| Lake View town | 789 | 782 | -7 | -0.89% |
| Lamar town | 1,015 | 991 | -24 | -2.36% |
| Lancaster city | 8,177 | 9,981 | 1,804 | 22.06% |
| Landrum city | 2,472 | 2,615 | 143 | 5.78% |
| Lane town | 585 | 516 | -69 | -11.79% |
| Latta town | 1,410 | 1,478 | 68 | 4.82% |
| Laurens city | 9,916 | 9,599 | -317 | -3.20% |
| Lexington town | 9,793 | 15,901 | 6,108 | 62.37% |
| Liberty city | 3,009 | 3,064 | 55 | 1.83% |
| Lincolnville town | 904 | 842 | -62 | -6.86% |
| Little Mountain town | 255 | 260 | 5 | 1.96% |
| Livingston town | 148 | 142 | -6 | -4.05% |
| Lockhart town | 39 | 490 | 451 | 1,156.41% |
| Lodge town | 114 | 112 | -2 | -1.75% |
| Loris city | 2,079 | 2,351 | 272 | 13.08% |
| Lowndesville town | 166 | 159 | -7 | -4.22% |
| Lowrys town | 207 | 198 | -9 | -4.35% |
| Luray town | 115 | 112 | -3 | -2.61% |
| Lyman town | 2,659 | 2,870 | 211 | 7.94% |
| Lynchburg town | 588 | 553 | -35 | -5.95% |
| Manning city | 4,025 | 3,943 | -82 | -2.04% |
| Marion city | 7,042 | 6,801 | -241 | -3.42% |
| Mauldin city | 15,224 | 21,784 | 6,560 | 43.09% |
| Mayesville town | 1,001 | 1,007 | 6 | 0.60% |
| McBee town | 714 | 706 | -8 | -1.12% |
| McClellanville town | 459 | 496 | 37 | 8.06% |
| McColl town | 2,498 | 2,308 | -190 | -7.61% |
| McConnells town | 287 | 367 | 80 | 27.87% |
| McCormick town | 1,489 | 2,660 | 1,171 | 78.64% |
| Meggett town | 1,230 | 1,363 | 133 | 10.81% |
| Moncks Corner town | 5,952 | 7,044 | 1,092 | 18.35% |
| Monetta town | 220 | 217 | -3 | -1.36% |
| Mount Croghan town | 155 | 152 | -3 | -1.94% |
| Mount Pleasant town | 47,609 | 65,472 | 17,863 | 37.52% |
| Mullins city | 5,029 | 4,716 | -313 | -6.22% |
| Myrtle Beach city | 22,759 | 30,596 | 7,837 | 34.43% |
| Neeses town | 413 | 395 | -18 | -4.36% |
| New Ellenton town | 2,250 | 2,227 | -23 | -1.02% |
| Newberry city | 10,580 | 10,907 | 327 | 3.09% |
| Nichols town | 408 | 396 | -12 | -2.94% |
| Ninety Six town | 1,936 | 1,921 | -15 | -0.77% |
| Norris town | 847 | 852 | 5 | 0.59% |
| North Augusta city | 17,574 | 20,712 | 3,138 | 17.86% |
| North Charleston city | 79,641 | 94,407 | 14,766 | 18.54% |
| North Myrtle Beach city | 10,974 | 15,816 | 4,842 | 44.12% |
| North town | 813 | 776 | -37 | -4.55% |
| Norway town | 389 | 367 | -22 | -5.66% |
| Olanta town | 613 | 627 | 14 | 2.28% |
| Olar town | 237 | 212 | -25 | -10.55% |
| Orangeburg city | 12,765 | 13,224 | 459 | 3.60% |
| Pacolet town | 2,690 | 2,825 | 135 | 5.02% |
| Pageland town | 2,521 | 2,513 | -8 | -0.32% |
| Pamplico town | 1,139 | 1,154 | 15 | 1.32% |
| Parksville town | 120 | 115 | -5 | -4.17% |
| Patrick town | 354 | 347 | -7 | -1.98% |
| Pawleys Island town | 138 | 141 | 3 | 2.17% |
| Paxville town | 248 | 244 | -4 | -1.61% |
| Peak town | 61 | 96 | 35 | 57.38% |
| Pelion town | 553 | 593 | 40 | 7.23% |
| Pelzer town | 97 | 103 | 6 | 6.19% |
| Pendleton town | 2,966 | 3,119 | 153 | 5.16% |
| Perry town | 237 | 239 | 2 | 0.84% |
| Pickens city | 3,012 | 3,026 | 14 | 0.46% |
| Pine Ridge town | 1,593 | 1,985 | 392 | 24.61% |
| Pinewood town | 459 | 482 | 23 | 5.01% |
| Plum Branch town | 98 | 94 | -4 | -4.08% |
| Pomaria town | 177 | 181 | 4 | 2.26% |
| Port Royal town | 3,950 | 11,064 | 7,114 | 180.10% |
| Prosperity town | 1,047 | 1,059 | 12 | 1.15% |
| Quinby town | 842 | 867 | 25 | 2.97% |
| Ravenel town | 2,214 | 2,288 | 74 | 3.34% |
| Reevesville town | 207 | 211 | 4 | 1.93% |
| Reidville town | 478 | 524 | 46 | 9.62% |
| Richburg town | 332 | 312 | -20 | -6.02% |
| Ridge Spring town | 823 | 781 | -42 | -5.10% |
| Ridgeland town | 2,518 | 2,589 | 71 | 2.82% |
| Ridgeville town | 1,690 | 1,984 | 294 | 17.40% |
| Ridgeway town | 328 | 328 | 0 | 0.00% |
| Rock Hill city | 49,765 | 67,339 | 17,574 | 35.31% |
| Rockville town | 137 | 131 | -6 | -4.38% |
| Rowesville town | 378 | 360 | -18 | -4.76% |
| Ruby town | 348 | 341 | -7 | -2.01% |
| Salem town | 126 | 132 | 6 | 4.76% |
| Salley town | 410 | 414 | 4 | 0.98% |
| Saluda town | 3,066 | 2,910 | -156 | -5.09% |
| Santee town | 740 | 718 | -22 | -2.97% |
| Scotia town | 227 | 221 | -6 | -2.64% |
| Scranton town | 942 | 1,032 | 90 | 9.55% |
| Seabrook Island town | 1,250 | 1,202 | -48 | -3.84% |
| Sellers town | 277 | 261 | -16 | -5.78% |
| Seneca city | 7,652 | 8,038 | 386 | 5.04% |
| Sharon town | 421 | 504 | 83 | 19.71% |
| Silverstreet town | 216 | 225 | 9 | 4.17% |
| Simpsonville city | 14,352 | 17,144 | 2,792 | 19.45% |
| Six Mile town | 553 | 582 | 29 | 5.24% |
| Smoaks town | 140 | 134 | -6 | -4.29% |
| Smyrna town | 59 | 80 | 21 | 35.59% |
| Snelling town | 246 | 239 | -7 | -2.85% |
| Society Hill town | 700 | 685 | -15 | -2.14% |
| South Congaree town | 2,266 | 2,370 | 104 | 4.59% |
| Spartanburg city | 39,673 | 39,584 | -89 | -0.22% |
| Springdale town | 2,877 | 2,939 | 62 | 2.16% |
| Springfield town | 504 | 482 | -22 | -4.37% |
| St. George town | 2,092 | 2,121 | 29 | 1.39% |
| St. Matthews town | 2,107 | 1,948 | -159 | -7.55% |
| St. Stephen town | 1,776 | 1,778 | 2 | 0.11% |
| Starr town | 173 | 199 | 26 | 15.03% |
| Stuckey town | 263 | 233 | -30 | -11.41% |
| Sullivan's Island town | 1,911 | 1,870 | -41 | -2.15% |
| Summerton town | 1,061 | 1,028 | -33 | -3.11% |
| Summerville town | 27,752 | 45,193 | 17,441 | 62.85% |
| Summit town | 219 | 263 | 44 | 20.09% |
| Sumter city | 39,643 | 38,625 | -1,018 | -2.57% |
| Surfside Beach town | 4,425 | 4,783 | 358 | 8.09% |
| Swansea town | 533 | 799 | 266 | 49.91% |
| Sycamore town | 185 | 171 | -14 | -7.57% |
| Tatum town | 69 | 62 | -7 | -10.14% |
| Tega Cay city | 4,044 | 5,014 | 970 | 23.99% |
| Timmonsville town | 2,315 | 2,373 | 58 | 2.51% |
| Travelers Rest city | 4,099 | 4,523 | 424 | 10.34% |
| Trenton town | 226 | 270 | 44 | 19.47% |
| Troy town | 105 | 107 | 2 | 1.90% |
| Turbeville town | 602 | 707 | 105 | 17.44% |
| Ulmer town | 102 | 94 | -8 | -7.84% |
| Union city | 8,793 | 8,039 | -754 | -8.58% |
| Vance town | 208 | 199 | -9 | -4.33% |
| Varnville town | 2,074 | 2,042 | -32 | -1.54% |
| Wagener town | 863 | 875 | 12 | 1.39% |
| Walhalla city | 3,801 | 3,576 | -225 | -5.92% |
| Walterboro city | 5,153 | 5,780 | 627 | 12.17% |
| Ward town | 110 | 105 | -5 | -4.55% |
| Ware Shoals town | 2,363 | 2,348 | -15 | -0.63% |
| Waterloo town | 203 | 201 | -2 | -0.99% |
| Wellford city | 2,030 | 2,465 | 435 | 21.43% |
| West Columbia city | 13,064 | 13,914 | 850 | 6.51% |
| West Pelzer town | 879 | 915 | 36 | 4.10% |
| West Union town | 297 | 301 | 4 | 1.35% |
| Westminster city | 2,743 | 2,663 | -80 | -2.92% |
| Whitmire town | 1,512 | 1,528 | 16 | 1.06% |
| Williams town | 116 | 116 | 0 | 0.00% |
| Williamston town | 3,791 | 3,964 | 173 | 4.56% |
| Williston town | 3,307 | 3,190 | -117 | -3.54% |
| Windsor town | 127 | 131 | 4 | 3.15% |
| Winnsboro town | 3,599 | 3,577 | -22 | -0.61% |
| Woodford town | 196 | 188 | -8 | -4.08% |
| Woodruff city | 4,229 | 4,103 | -126 | -2.98% |
| Yemassee town | 807 | 860 | 53 | 6.57% |
| York city | 6,985 | 7,967 | 982 | 14.06% |
Source: Population Division, U.S. Census Bureau